A comic-book artist meets a woman on the NY streets, but after a quick flirtation, she suddenly collapses, and is picked-up by an old ambulance. He checks all the hospitals in the area, but the woman seems to have disappeared.
For her first day of orientation, Dr. Tristian Mackenzie makes her way to the Silverdale Psychiatric Hospital for the criminally insane, where she learns of the strange series of cases from the similarly strange Dr. Moon.
