采访在第二季中继续进行。2022年，吸血鬼Louis de Pointe du Lac（雅各布·安德森 Jacob Anderson 饰）向记者Daniel Molloy（埃里克·博高森 Eric Bogosian 饰）讲述着他的人生故事。于1940年密谋杀害了吸血鬼Lestat de Lioncourt（萨姆·里德 Sam Reid 饰）后，Louis和新手吸血鬼少女Claudia （德莱尼·海勒斯 Delainey Hayles 饰）踏上了欧洲的冒险旅程，两人一起探寻旧世界吸血鬼和巴黎的吸血鬼剧院。正是在巴黎，Louis第一次遇见了吸血鬼Armand（阿萨德·扎曼 Assad Zaman 饰）。事实证明，他们之间的求爱和性关系会在过去和未来造成毁灭性的后果，而Molloy将探寻埋藏在记忆中的真相。
After being wheelchair-bound from a crash, María José "Santita" Cano left her love at the altar. 20 years later, his return makes her face her past choices and test the limits of her love.
After attending a medical conference in Beijing and coming frighteningly close to dying in a car crash, Dr Matthew Nolan, played by Armitage (Obsession, Stay Close) arrives home and is immediately arrested at London’s Heathrow Airport. Exhausted and confu
